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In a further aspect, and addition to the aforementioned, invention comprises a pharmaceutical composition comprising lovastatin 1a. In particular, the pharmaceutically active composition comprising lovastatin 1a is formulated as a film-forming material.
In a further aspect, the invention comprises a pharmaceutical composition comprising lovastatin 1a and bovine antirrhythmic hormone (AHR), a compound which stimulates release of the AHR after co-administration with lovastatin 1a and for co-administration with another compound the treatment of coronary heart disease. The AHR is a co-administered compound in the treatment of congestive heart failure and as a preventive measure after an MI and a stroke.
In another aspect, the invention comprises a prophylactic composition comprising lovastatin 1a and AHR. In particular, the prophylactic composition is administered to a child having type 1 or 2 diabetes mellitus aged 3–11 years who is also receiving an anti-diabetic medication from at least 12 weeks of age.
In view of the above, it has been understood by those skilled in the art that compounds, alone or together, present a broad spectrum of anti-cancer activity and can be administered as orally products.
The invention includes specific and preferred features. While it has been described herein with reference to FIGS. 1A and 1C, in some cases the embodiments are intended to be illustrative and not limiting. In such instances, the descriptions are to be regarded Atorva 2mg $92.66 - $0.77 Per pill as exemplary and not limiting. Furthermore, while specific embodiments are illustrated and described herein may by taken out way of illustration and not by way of limitation, the present disclosure is not so limited and necessarily to them.
While certain specific embodiments have been described, variations or modifications thereof can readily be employed without departing from the subject matter. Accordingly, details of the embodiments set forth above are to be regarded as a guide only, and should not be construed to limiting.
Moreover, it should be understood that the terms "comprising" and "comprising a portion of" are defined to mean possessing some quantity, at least a sufficient quantity for one or more desired characteristics, and "comprises", "comprising one or more," and more than" are intended to be inclusive and not exclusive. A new study by researchers from the Massachusetts Institute of Technology (MIT) and the University of Virginia shows that a relatively rare form of brain cancer can be treated using a drug derived from protein that can destroy cancer cells.
Molecular biologist and neurosurgeon Jef Boeke, Ph.D., of MIT's Koch Institute for Integrative Cancer Research, and colleagues report their findings today in the journal Nature Medicine.
The cancer cells are found to be "dopamine neurons," cells that are responsible for learning and sensation are thought to be involved in certain forms of brain disease.
Although atorvastatin 20 mg filmtabletten the investigators still don't fully understand how they kill off these dopamine neurons, the finding sheds light on basic mechanism of how cancerous cells are eradicated.
The researchers chose to target a class of protein called Dicer, which is present on dopamine neurons in a variety of human brain cancers. Previous work has shown that Dicer, also known as DIC2,
1 mg finpecia for hair loss induces the death of cancer cells through a process called mitochondrial fission.
"In the case of this particular cancer, we took a molecular approach, specifically targeting DIC2," said Boeke. "We're now using that knowledge in our efforts to develop drugs that would be effective against a whole variety of cancers. For example, if we want to target one form of melanoma, we might be able to target a different type of cancer cells with another drug that targets specific DIC2."
To understand how the researchers killed dopamine neurons by targeting Dicer, Boeke's group turned to yeast experiments.
The researchers first identified a population of DIC2 mutants, which produce a protein called DIC1 that is essential for DIC2 expression. They also found that mutations in DIC2 cause a disease called "DIC2-driven epilepsy," which is characterized by seizures and other neurological effects within five days.
"The ability to study a new type of cancer that produces this rare mutation for which there are no treatments makes us much closer to understanding this disease," Boeke said. "In addition, by uncovering the precise cellular mechanism behind DIC2-driven epilepsy, we may be able to develop drug-based approaches, such as blocking DIC2, that can target this very specific neural cell type and also help develop new, potentially targeted therapies against other types of cancer."
Boeke's coauthors are former Koch Institute postdocs Hsiang-Hui Kuo and Peter Zu. Their work helped advance the creation.
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See also: Aminophylline (in more detail)
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